Basic Medicine, Oncology, Immunology

Tumor Immunobiology (Miyagi Cancer Center)

Medical Sciences Course

  • Master / Doctoral Degree

Faculty

TANAKA,NobuyukiTANAKA,Nobuyuki
TANAKA,Nobuyuki

Professor, M.D. Ph.D.

*Concurrent Position

Research Theme

Research Keywords:

Technical Keywords:

Laboratory Introduction

Identification of genes that regulate Cancer Stem Cells
Oncogenesis using model animals
Cancer stem cell maintenance mechanism
http://www.cbt.med.tohoku.ac.jp/english/
(http://www. miyagi-pho.jp/mcc/htdocs/kenkyu/soshiki-renkei.html)

Recent Publications

  • Oshima, R. et al. ESCRT-0 dysfunction compromises autophagic degradation of protein aggregates and facilitates ER stress-mediated neurodegeneration via apoptotic and necroptotic pathway. Scientific Reports 6, 24997 (2016)
  • Mochizuki, M. et al. CD271 regulates the proliferation and motility of hypopharyngeal cancer cell. Scientific Reports 6, 30707 (2016)
  • Kobayashi, EH. et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat Commun. 7:11624 (2016)
  • Tamai, K. et al. Suppressive expression of CD274 increases tumorigenesis and cancer stem cell phenotypes in cholangiocarcinom. Cancer Science 105, 667-674 (2014)
  • Watanuki, Z. et al. Synergistic cytotoxicity of afatinib and cetuximab against EGFR T790M involves Rab11-dependent EGFR recycling. Biochem Biophy Res Commun. 455, 269-276 (2014)