Nursing, Physiology

Science of Nursing Practice

To Challenge the Effects of Physiology and Immunology on Nursing Practice

Health Sciences Course

  • Master / Doctoral Degree


ASAKURA, Kyoko*Concurrent Position

Professor, R.N. Ph.D.

Research Theme

  • Physiological effects on nursing practice
  • Relationship between sexual hormone and autonomic nervous activity
  • Immunological analysis of skin wound healing
Research Keywords:

respiration, autonomic nervous activity, nursing care, wound healing, infection

Technical Keywords:

heart rate variability, animal experiment, immunology

Laboratory Introduction

The purpose of our research will build the scientific knowledge base of advancement of nursing practice. Evidence- based practice is nursing care provide that is supported by reliable research- based evidence. Our members are now a Professor, a Lecture and graduate students. Our research interests are as follows,
1) Physiological effects on nursing practice
2) The effect of sexual hormone on autonomic nervous activity
3) Immunological study of skin wound healing

Figure 1. Wound healing related factors

Figure 1. Wound healing related factors

Figure 2. Effects of microbial load on the wound healing

Figure 2. Effects of microbial load on the wound healing

Recent Publications

  • Sarina Bao, et al. Blunted Autonomic Responses and Low-Grade Inflammation in Mongolian Adults Born at Low Birth weight. Tohoku J Exp Med 240. 171-179, 2016
  • Tanno H, et al. Contribution of invariant natural killer T cells to skin wound healing. Am J Pathol 185(12): 3248-3257, 2015
  • Sasaki K, Maruyama R. Consciously controlled breathing decreases the high-frequency component of heart rate variability by inhibiting cardiac parasympathetic nerve activity. Tohoku J Exp Med. 233(3): 155-163, 2014
  • Kanno E, et al. Neutrophil-derived tumor necrosis factor-α contributes to acute wound healing promoted by N-(3-oxododecanoyl)-L-homoserine lactone from Pseudomonas aeruginosa. J Dermatol Sci. 70(2): 130-138, 2013
  • Kanno E, et al. Wound healing in skin promoted by inoculation with Pseudomonas aeruginosa PAO1: the critical role of tumor necrosis factor-α secreted from infiltrating neutrophils. Wound Rep Regen. 19(5): 608-621, 2011