2023.03.03
Press Release
Acid glia in REM sleep: Stronger Acid Response in Epileptic Mice
Researchers at Tohoku University have shown that astrocytes – star-shaped glial cells that control the local ionic and metabotropic environment of the brain – exhibit an acid response with REM sleep in mice. They theorize that the acid response could be the underlying drive for specific information processing and generating plasticity during sleep.
They further discovered that REM response in astrocytes intensified in the epileptic brain, meaning studying brain environmental changes associated with REM sleep could potentially be employed as a biomarker for the severity of epileptogenesis.
The findings were detailed in the journal Brain on March 3, 2023.
TOHOKU UNIVERSITY Research News
Publication Details:
Title: Properties of REM sleep alterations with epilepsy
Authors: Yoko Ikoma, Yusuke Takahashi, Daichi Sasaki, Ko Matsui
Journal: Brain
DOI: doi.org/10.1093/brain/awac499
https://doi.org/10.1093/brain/awac499
Contact:
Name: Ko Matsui
Affiliation: Super-network Brain Physiology, Graduate School of Life Sciences, Tohoku University
Email: matsui@med.tohoku.ac.jp
Website: http://www.ims.med.tohoku.ac.jp/matsui/