Press Release

Researchers at Tohoku University have discovered that there are two parallel processes involved in memory formation when a mouse performs a motor learning task. One process occurs during training and is called online learning, while the other happens during the resting period and is called offline learning. Online learning can be boosted or reduced by manipulating glial activity, but offline learning remains unaffected by these manipulations. Understanding the cellular mechanisms underlying these independent parallel memory formation processes may lead to the development of efficient rehabilitation after strokes, dementia treatment, or realizing extended intelligence.

The findings were detailed in the journal Glia on June 27, 2023.

TOHOKU UNIVERSITY Research News

Publication Details:
Title:        Glial modulation of the parallel memory formation
Authors: Teppei Kanaya, Ryo Ito, Yosuke M. Morizawa, Daichi Sasaki, Hiroki Yamao, Hiroshi Ishikane, Yuichi Hiraoka, Kohichi Tanaka, and Ko Matsui
Journal:  Glia
DOI: https://doi.org/10.1002/glia.24431
Embargo date: June 27, 2023

Contact: 
Name:        Ko Matsui
Affiliation:   Super-network Brain Physiology, Graduate School of Life Sciences,Tohoku University
Email:         matsui@med.tohoku.ac.jp
Website:     http://www.ims.med.tohoku.ac.jp/matsui/