Member
Toshio Iijima (Neuroscience)
Graduated from the Doctorial Course in the Graduate School of Science, Tohoku University. Worked as Research Assistant Professor at the University of California Los Angeles, researcher at the Electrotechnical Laboratory, Ministry of International Trade and Industry (present National Institute of Advanced Industrial Science and Technology (AIST)), Manager of the Biofunction Research Office, Chief Research Officer, professor at the University of Tsukuba Medical Branch, etc. and became professor at Tohoku University Graduate School of Life Science. Vice-President of Tohoku University( Life Sciences and Research ethics),Dean of Tohoku University Graduate School of Life Sciences. Councilor of Tohoku University. Received the Hiroshi Irisawa Memorial JJP Award from the Physiological Society of Japan (1998), etc
- Introduction of Research
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Understanding of our mind has long been a big subject of human beings. Recent advances of analytical technique for the brain mechanisms may allow us to answer the question ｡ﾈwhat is mind｡ﾉ in the near future, through the knowledge of the brain now being accumulated. On the way to the final goal, it seems to be essential for us to elucidate the functional architecture of the brain for the better understanding of the brain. Based on this concept, we are studying the neuronal bases of higher brain function, such as the learning and memory, the motor control and the processing of various sensory inputs. In addition, the developments of new technique with virus vectors and of the brain machine interface are now going on.
A high-speed real-time optical imaging of neural activity in the MI of monkey during target reaching hand movement
Studies of neuronal circuit with newly developed trans-synaptic tracing method using virus vectors
Propagation of neural activity in the entorhinal-hippocampal slice preparation visualized with a high-speed optical imaging
- Articles
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- Ishikawa T, Sato T, Shimizu A, Tsutsui K, de Curtis M, Iijima T.: Odor-driven activity in the olfactory cortex of an in vitro isolated Guinea pig whole brain with olfactory epithelium. J. Neurophysiol. 97, 670-679(2007)
- Kajiwara, R., Takashima, I., Witter, M.P., Mimura, Y., Iijima, T.: Amygdala input promotes the spread of excitatory neural activity from the perirhinal cortex to the entorhinal/hippocampal neurocircuit: An optical imaging study. J. Neurophysiol. 89, 2176-2184 (2003)
- Iijima, M.P. Witter, M. Ichikawa, T. Tominaga, R. Kajiwara and G. Matsumoto; Entorhinal-Hippocampal Interactions Revealed by Real-Time Imaging. Science 272, 1069-1232 (1996)
- Vranesic, T. Iijima, M. Ichikawa, G. Matsumoto, T. Knopfel: Signal transmission in the parallel fiber-Purkinje cell system visualized by high-resolution imaging. Proc. Natl. Acad. Sci. USA, 91, 13014-13017 (1994)
- Iijima, S. Ciani and S. Hagiwara: Effect on the external pH on Ca Channels: Experimental studies and theoretical considerations using a two-site, two ion model. Proc. Natl. Acad. Sci. USA 83, 654-658 (1987)