医科学専攻
- Doctoral Courses
博士課程
Feto-Maternal Medical Science（Environment and Genome Research Center）母児医科学（環境遺伝医学総合研究センター）
STAFF
Professor
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Miura, YuichiroProfessor. 三浦 雄一郎 教授
CONTACT
TEL：＋81-22-717-7893
E-MAIL：yuichiro.miura.c4*tohoku.ac.jp
（「*」を「@」に変換してください）
OUTLINE
The aim of our laboratory is to clarify the factors that affect the child development through following cohort studies.
1. The Japan Environment and Children’s Study (JECS)
We participate in JECS and are responsible for the participants in the Miyagi area. JECS is an ongoing nationwide and government funded birth cohort. Approximately 100,000 expecting mothers were recruited in designated 15 areas between January 2011 and March 2014. The mothers and their children have been followed regularly since then. This birth cohort study is aimed at investigating the influence of environmental factors including chemical substances such as Per- and Polyfluoroalkyl Substances (PFAS), lead, mercury, and nicotine on the health and development of children.
2. Premature birth cohort
All infants who were born in the Miyagi prefecture and whose birth weight were < 1,250 g have been registered and regularly checked up their growth and development since 2005. Their gestational age, birth weight, and treatment histories have been recorded and accumulated. Using this database, we explore causal relationship between developmental disorder in later life and perinatal environmental factors including premature birth itself, several morbidities such as chronic lung disease and patent ductus arteriosus, and medical practice.
私たちの研究室では、以下のコホート研究を通してこどもの発達に影響を及ぼす要因を明らかにすることを目指しています。
1. エコチル調査
環境省が主導するエコチル調査という大規模出生コホート調査に参加し、宮城県内の調査を担当しています。この調査では、日本中の15の地域からおよそ100,000組のお母さんとお子さんに参加していただき、質問票への回答や身体計測値，血液・尿検査結果などのデータを集めています。この調査を通じて、有機フッ素化合物 (PFAS)、鉛、水銀、ニコチンなどの化学物質を含めたお子さんを取り巻く環境の様々な要因が、健康・発達に対してどのような影響を及ぼすのかを調べています。
2. さとめんこ事業
2005年以降、宮城県では1,250 g未満で出生した全てのお子さんに対して定期的に発育・発達のフォローアップを行っています。また妊娠週数や出生体重、新生児集中治療の内容も記録しています。このデータベースを用いて、早産出生そのもの、慢性肺疾患や動脈管開存症などの病態、さらにはそれらに対する医療行為など出生前後の環境因子が将来的な発達障害にどのように関連するかを調べています。
The webpage of Eco & Child Miyagi Unit Center
エコチル宮城ユニットセンターのHP
A scene from a research meeting
研究ミーティングの一場面
Research presentations at open campus
オープンキャンパスでの成果発表
ARTICLE
Miura, Y., et al. A cross-sectional study investigating the association between parental daily brushing, extended breastfeeding, or parental smoking habit and early childhood dental caries in 4-year-old children: the Japan Environment and Children’s Study. BMC Pediatr 2025 Aug 8;25(1):613.
Tagami, K., et al. Advanced maternal age is a risk factor for both early and late gestational diabetes mellitus: The Japan Environment and Children’s Study. J Diabetes Investig 16(4):735-743, 2025.
Tsuchiya, M., et al. Prospective association of daily toothbrushing frequency and the prevalence of childhood functional constipation: the Japan Environment and Children’s Study. Sci Rep Mar 5;15(1):7753, 2025.
Itoh, S., et al. Eryhema nodosum as the initial symptom of Crohn’s disease: A case report. Pediatr Int 65(1):e15626, 2023.
Ono, T., et al. Ductus Arteriosus of Extremely Preterm Twins is More Resistant to Cyclooxygenase Inhibitors Than Those of Singletons. Pediatr Cardiol 43(3):624-630, 2022.
