東北大学大学院医学系研究科・医学部

STAFF

Professor

• Ohmagari, NorioProfessor. 大曲 貴夫 客員教授
  

CONTACT

OUTLINE

The field of infectious diseases has greatly expanded from the health problems of individual patients to the global level. It covers not only the diagnosis and treatment of individual diseases, but also prevention and public health measures. The Disease Control and Prevention Center (DCC) at the National Center for Global Health and Medicine (NCGM) will 1) function as a clinical referral center for clinical infectious diseases, 2) focus on human resource development and training in the field of infectious diseases, 3) serve as a source of information and networking, 4) serve as a research center for infectious diseases in Japan and abroad, and 5) conduct field epidemiological studies.
We are engaged in comprehensive, multifaceted, and advanced activities related to infectious diseases in Japan and overseas. Our main research themes include genome-based diagnosis of emerging and reemerging infectious diseases, treatment and prevention of emerging and reemerging infectious diseases, emerging preparedness of medical institutions and public health, psychosocial factors involved in infectious disease epidemics and risk communication methods, antimicrobial-resistant bacterial infections, malaria and dengue. and clinical epidemiology of imported infectious diseases such as malaria, dengue fever, and typhoid fever.

感染症のフィールドは、個人の患者の健康の問題からグローバルレベルへと大きく広がっています。対象は、個別の疾患の診断治療のみならず、予防・公衆衛生的な対策まで多岐にわたります。国立国際医療研究センター　国際感染症センター（DCC）では1) 臨床感染症のclinical referral centerとして機能する、2)感染症領域の人材育成/トレーニングへの注力、3)情報の発信源となりネットワーキングに努める、4)国内外の感染症の研究拠点となる、5)実地疫学の実践の5つを活動の柱に据え、国内・国外の感染症に関す包括的・多面的・先進的な取り組みを行っています。主な研究テーマとしては、新興再興感染症のゲノム手法を用いた診断、新興再興感染症の治療・予防、医療機関および公衆衛生のEmerging Preparedness、感染症の流行に関与する心理社会的因子およびリスクコミュニケーションの手法に関する研究、抗菌薬耐性菌感染症、マラリア・デング熱・腸チフスなどの輸入感染症の臨床疫学研究です。

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  Gimsa-stained image of Plasmodium falciparum malariae.
  熱帯熱マラリア原虫のギムザ染色像

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  Emerging infectious disease response training
  新興感染症対応訓練の様子

ARTICLE

Beigel JH, et al.; ACTT-1 Study Group Members. Remdesivir for the Treatment of Covid-19 - Final Report. N Engl J Med. 2020 Nov 5;383(19):1813-1826. doi: 10.1056/NEJMoa2007764. Epub 2020 Oct 8. PMID: 32445440; PMCID: PMC7262788.

Grein J , et al. Compassionate Use of Remdesivir for Patients with Severe Covid-19. N Engl J Med. 2020 Jun 11;382(24):2327-2336. doi: 10.1056/NEJMoa2007016. Epub 2020 Apr 10. PMID: 32275812; PMCID: PMC7169476.

Kutsuna S, et al. Autochthonous dengue fever, Tokyo, Japan, 2014. Emerg Infect Dis. 2015 Mar;21(3):517-20. doi: 10.3201/eid2103/141662. PubMed PMID: 25695200; PubMed Central PMCID: PMC4344289.

Hayakawa K, et al. Molecular and epidemiological characterization of IMP-type metallo-β-lactamase-producing Enterobacter cloacae in a Large tertiary care hospital in Japan. Antimicrob Agents Chemother. 2014 Jun;58(6):3441-50. doi: 10.1128/AAC.02652-13. Epub 2014 Apr 7. PubMed PMID: 24709261; PubMed Central PMCID: PMC4068452.

Kutsuna S, et al. The usefulness of serum C-reactive protein and total bilirubin levels for distinguishing between dengue fever and malaria in returned travelers. Am J Trop Med Hyg. 2014 Mar;90(3):444-8. doi: 10.4269/ajtmh.13-0536. Epub 2014 Jan 13. PubMed PMID: 24420780; PubMed Central PMCID: PMC3945689.