医科学専攻
- Doctoral Courses
博士課程
Laboratory of Oncology, Pharmacy Practice and Sciences（Graduate School of Pharmaceutical Sciences）がん化学療法薬学（薬学研究科）
STAFF
Professor
-
Tomioka,YoshihisaProfessor. 富岡 佳久 教授
Other Faculty / Staff
-
Matsumoto, Yotaro
Lect. 松本 洋太郎 講師 -
Akiyama, Yasutoshi
Assistant Prof. 秋山 泰利 助教
CONTACT
TEL：＋81-22-795-6851
E-MAIL：yoshihisa.tomioka.a6*tohoku.ac.jp
（「*」を「@」に変換してください）
OUTLINE
・Research on optimization of cancer chemotherapy
・Development of educational programs to train supergeneralist pharmacist
・Research and development of new diagnostic methods for cancer
・Discovery of novel therapeutic agents for cancer immunotherapy
・Development and application of a comprehensive quantitative method for modified nucleosides
・Research on RNA-mediated cellular stress response
・がん化学療法至適化に関する研究
・スーパージェネラリスト・ファーマシスト育成の教育プログラム開発
・がんの新規診断鑑別法の開発
・がん免疫を標的とする新規治療薬の創製
・修飾ヌクレオシドの網羅的精密定量法の開発と臨床応用
・RNAを介した細胞のストレス応答メカニズムの解明
liquid chromatograph-mass spectrometer (LC-MS)
液体クロマトグラフ質量分析計（LC-MS）
Ultraviolet-visible detector
紫外可視検出器
LC-MS experiment scene
実際の測定の様子
ARTICLE
Akiyama Y, et al. Oxidative stress, tRNA metabolism and protein synthesis. Antioxidants & Redox Signaling 40, 10-12, 2024. doi: 10.1089/ars.2022.0206
URL：https://doi.org/10.1089/ars.2022.0206
Kujirai R, et al. Development of a LC–MS/MS analytical method of 15 compounds related to renal function for a prognostic method of progression risk in patients with diabetic kidney disease. Journal of Pharmaceutical and Biomedical Analysis Open 2:100021, 2023. doi: 10.1016/j.jpbao.2023.100021
URL：https://doi.org/10.1016/j.jpbao.2023.100021
Yamasaki A, et al. CD98 regulates the phosphorylation of HER2 and a bispecific anti-HER2/CD98 antibody inhibits the growth signal of human breast cancer cells. Genes to Cells 28:374–382, 2023. doi: 10.1111/gtc.13016
URL：https://doi.org/10.1111/gtc.13016
Yamasaki A, et al. Dual-targeting therapy against HER3/MET in human colorectal cancers. Cancer Medicine 12: 9684–9696, 2023. doi: 10.1002/cam4.5673
URL：https://doi.org/10.1002/cam4.5673
Akiyama Y, et al. RTCB Complex Regulates Stress-Induced tRNA Cleavage. Int. J. Mol. Sci. 23:13100, 2022. doi: 10.3390/ijms232113100
URL：https://doi.org/10.3390/ijms232113100
