医科学専攻
- Doctoral Courses
博士課程
Laboratory of Oncology, Pharmacy Practice and Sciencesがん化学療法薬学
STAFF
Professor
-
Tomioka,YoshihisaProfessor. 富岡 佳久 教授
Other Faculty / Staff
-
Matsumoto, Yotaro
Lect. 松本 洋太郎 講師 -
Akiyama, Yasutoshi
Assistant Prof. 秋山 泰利 助教
CONTACT
TEL：＋81-22-795-6851
E-MAIL：yoshihisa.tomioka.a6*tohoku.ac.jp
（「*」を「@」に変換してください）
OUTLINE
・Research on optimization of cancer chemotherapy
・Development of educational programs to train supergeneralist pharmacist
・Research and development of new diagnostic methods for cancer
・Discovery of novel therapeutic agents for cancer immunotherapy
・Development and application of a comprehensive quantitative method for modified nucleosides
・Research on RNA-mediated cellular stress response
・がん化学療法至適化に関する研究
・スーパージェネラリスト・ファーマシスト育成の教育プログラム開発
・がんの新規診断鑑別法の開発
・がん免疫を標的とする新規治療薬の創製
・修飾ヌクレオシドの網羅的精密定量法の開発と臨床応用
・RNAを介した細胞のストレス応答メカニズムの解明
liquid chromatograph-mass spectrometer (LC-MS)
液体クロマトグラフ質量分析計（LC-MS）
Ultraviolet-visible detector
紫外可視検出器
LC-MS experiment scene
実際の測定の様子
ARTICLE
Akiyama Y, et al. RTCB Complex Regulates Stress-Induced tRNA Cleavage. Int. J. Mol. Sci. 23:13100, 2022.
URL：https://doi.org/10.3390/ijms232113100
Akiyama Y, et al. Selective Cleavage at CCA Ends and Anticodon Loops of tRNAs by Stress-Induced RNases. Front Mol Biosci 9: 791094, 2022.
URL：https://doi.org/10.3389/fmolb.2022.791094
Nagai K, et al. Identification of novel biomarkers of hepatocellular carcinoma by high-definition mass spectrometry: Ultrahigh-performance liquid chromatography quadrupole time-of-flight mass spectrometry and desorption electrospray ionization mass spectrometry imaging. Rapid Commun Mass Spectrom. 34( S1):e8551: 2020.
URL：https://doi.org/10.1002/rcm.8551
Kanemitsu Y, et al. Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS. Sci Rep. 13;9(1):19075, 2019
URL：https://www.ncbi.nlm.nih.gov/pubmed/31836785
Kikuchi K, et al. Gut microbiome-derived phenyl sulfate contributes to albuminuria in diabetic kidney disease. Nat Commun 10:1835, 2019.
URL：https://doi.org/10.1038/s41467-019-09735-4
