保健学専攻
- Doctoral Courses
博士課程
Therapeutic Radiology放射線治療学
STAFF
Professor
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Takeda, KenProfessor. 武田 賢 教授
Other Faculty / Staff
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Takagi, Hisamichi
Teaching Associate. 高城 久道 助手
CONTACT
OUTLINE
In Japan, one in two people is diagnosed with "cancer" in their lifetime, and the number of morbidity and deaths continues to rise due to the aging of the population. With the aging of cancer patients, it is expected that radiation therapy, which has less burden on the body, will play an even greater role in future cancer treatment.
Radiation therapy is evolving at a remarkable rate, and high-precision radiotherapy such as stereotactic radiotherapy and intensity-modulated radiotherapy has reduced side effects and improved treatment results, and multidisciplinary treatment with surgery and chemotherapy. The spread is also a tailwind for radiation therapy.
This field emphasizes joint research with the Department of Radiation Oncology of Tohoku University and Radiation Therapy Workers at other institutions. Currently, we are conducting research aimed at further development of radiotherapy (basic research on adaptive radiotherapy that adapts to changes in the shape of organs and lesions during the irradiation period, research on predicting adverse events associated with radiotherapy, etc.). In the field of radiotherapy, we are conducting joint research with the Medical Physics Group of the Department of Radiation Oncology, Graduate School of Medicine, Tohoku University (see the URL below) and training medical physicists and radiotherapy specialists.
http://www.radiol.med.tohoku.ac.jp/medical-physics/
本邦では国民の2人に1人が一生の内に「がん」と診断され、人口の高齢化を背景にその罹患数と死亡数は上昇を続けています。がん患者の高齢化もあり、今後のがん治療では身体への負担が少ない放射線治療の役割が更に大きくなることが予想されます。
放射線治療は目覚ましい速度で発展しており、定位放射線治療、強度変調放射線治療などの高精度放射線治療では副作用の軽減と治療成績の向上がみられ、また手術や化学療法との集学的治療の普及も放射線治療の追い風となっています。
本分野は本学の放射線腫瘍学分野や他施設の放射線治療業務者との共同研究を重視しています。現在、放射線治療の更なる発展を目指した研究（照射期間中の臓器や病変の形状変化に適合する適応放射線治療の基礎研究や放射線治療に伴う有害事象を予測する研究等）を行っています。放射線治療学分野は、東北大学医学系研究科放射線腫瘍学分野医学物理グループ（以下のURLをご参照下さい）と共同研究および医学物理士や放射線治療専門放射線技師の養成を行っております。
http://www.radiol.med.tohoku.ac.jp/medical-physics/
laboratory
研究室
Dose distribution map of prostate cancer intensity-modulated radiotherapy
前立腺癌強度変調放射線治療の線量分布図
Dose distribution map of stereotactic radiotherapy for lung cancer
肺癌定位放射線治療の線量分布図
ARTICLE
Ishizawa M, et al. Development of a prediction model for head and neck volume reduction by clinical factors, dose-volume histogram parameters and radiomics in head and neck cancer. J Radiat Res. 2023 Jul 18:rrad052. doi: 10.1093/jrr/rrad052. Online ahead of print.
URL：https://academic.oup.com/jrr/advance-article/doi/10.1093/jrr/rrad052/7225900
Takeda K, et al. Clinical predictors of severe late urinary toxicity after curative intensity-modulated radiation therapy for localized prostate cancer. J Radiat Res. 2021 Aug 31. Online ahead of print.
URL：https://academic.oup.com/jrr/advance-article/doi/10.1093/jrr/rrab074/6359245
Harada T, et al. YC-1 sensitizes the antitumor effects of boron neutron capture therapy in hypoxic tumor cells. J Radiat Res. 2020 Jul 6;61(4):524-534.
URL：https://academic.oup.com/jrr/article/61/4/524/5829026
Takagi H, et al. Multi-atlas-based auto-segmentation for prostatic urethra using novel prediction of deformable image registration accuracy. Med Phys. 2020 Jul;47(7):3023-3031.
URL：https://aapm.onlinelibrary.wiley.com/doi/10.1002/mp.14154
Ishizawa Y, et al. A photon source model based on particle transport in a parameterized accelerator structure for Monte Carlo dose calculations. Med Phys. 2018 Jul;45(7):2937-2946.
URL：https://aapm.onlinelibrary.wiley.com/doi/10.1002/mp.12976
