医科学専攻

  • Master's Courses 
    修士課程
  • Doctoral Courses 
    博士課程

Molecular Epidemiology分子疫学

  • 分子疫学
  • 肥満
  • がん
  • 自閉スペクトラム症
  • ゲノムコホート

STAFF

Professor

  • Kuriyama, ShinichiProfessor. 栗山 進一 教授 (兼任)

Other Faculty / Staff

  • Obara, Taku
    Assoc. Prof. 小原 拓 准教授
  • Ishikuro, Mami
    Lect. 石黒 真美 講師
  • Murakami, Keiko
    Lect. 村上 慶子 講師
  • Ueno, Fumihiko
    Assistant Prof. 上野 史彦 助教

CONTACT

TEL:+81-22-714-8104
E-MAIL:secretary*molepi.megabank.tohoku.ac.jp
(「*」を「@」に変換してください)

OUTLINE

Molecular epidemiology is a new interdisciplinary field in which genomic medicine and artificial intelligence technologies are combined with the foundation provided by epidemiology. We aim to unravel the interaction between genetics and the environment by utilizing genomic and omics information and applying artificial intelligence analysis technologies while using epidemiological methods. Our goal is to use these molecular epidemiological methods to recover missing heritability and to overcome multifactorial diseases, which have been a challenge for the world for many years. A disease derived from one disease concept may in fact be composed of many subgroups, each of which could have their own diverse cause and therapeutic effects. Therefore, multifactorial diseases may actually be multi-disease diseases.

分子疫学は疫学を基礎としそこにゲノム医学や人工知能解析技術などが融合した新たな学際的領域です。疫学手法を用いながら、ゲノム情報やオミックス情報を人工知能解析技術などを駆使して、遺伝・環境相互作用の解明を目指します。この分子疫学的手法を用いて、自閉スペクトラム症をはじめとする多因子疾患の病態を解明し、失われた遺伝率の回復とともに、これまで永年にわたっててこずってきた多因子疾患の克服を目指します。疾患によってはひとつの疾患概念でくくっていたものが実は多くのサブグループからなり、それぞれ原因や治療効果が異なっている可能性があります。多因子疾患は実は多病気疾患であるのかもしれないと考えています。

  • Laboratory members
    研究室員集合写真

  • Seminar
    セミナー風景

ARTICLE

Murakami K, et al. Factors associated with postpartum smoking relapse among women who quit in early pregnancy: the Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study. Journal of Epidemiology, 2021
URL:https://pubmed.ncbi.nlm.nih.gov/33907065/

Kuriyama S, et al. Cohort Profile: Tohoku Medical Megabank Project Birth and Three-Generation Cohort Study (TMM BirThree Cohort Study): rationale, progress and perspective. Int J Epidemiol. 49(1):18-19m, 2020
URL:https://pubmed.ncbi.nlm.nih.gov/31504573/

Yonezawa Y, et al. Fruit and vegetable consumption before and during pregnancy and birth weight of new-borns in Japan: the Tohoku medical megabank project birth and three-generation cohort study. Nutrition Journal. 19 (1): 80, 2020
URL:https://pubmed.ncbi.nlm.nih.gov/32746847/

Narita A, et al. Clustering by phenotype and genome-wide association study in autism. Translational Psychiatry. 10 (1): 290, 2020
URL:https://pubmed.ncbi.nlm.nih.gov/32807774/

Kuriyama S. Introduction to molecular epidemiology: Basic Knowledge of precision medicine. Tohoku University Press, Sendai, 2020[Jpn]

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