研究成果

  • ・Brozzi F, Diraison F, Lajus S, Rajatileka S, Philips T, Regazzi R, Fukuda M, Verkade P, Moln醇@r E, and Varadi A.
    Molecular mechanism of myosin Va recruitment to dense core secretory granules. Traffic 13, 54-69.2012
  • ・Ohbayashi N, Maruta Y, Ishida M, and Fukuda M.
    Melanoregulin regulates retrograde melanosome transport through interaction with the RILP p150Glued complex in melanocytes. J. Cell Sci., in press.2012
  • ・Ohbayashi N, Yatsu A, Tamura K, and Fukuda M.
    The Rab21-GEF activity of Varp, but not its Rab32/38 effector function, is required for dendrite formation in melanocytes. Mol. Biol. Cell, in press.2012
  • ・Chesneau L, Dambournet D, Machicoane M, Kouranti I, Fukuda M, Goud G, and Echard A.
    An ARF6/Rab35 GTPase cascade for endocytic recycling and successful cytokinesis. Curr. Biol., in press.2012
  • ・Fukuda M .
    Slp (synaptotagmin-like protein) Encyclopedia of Signaling Molecules 1st Edition (Choi, S. ed.) Springer, Berlin Heidelberg,Germany, in press.2012
  • ・Tamura K, Ohbayashi N, Ishibashi K, and Fukuda M.
    Structure-function analysis of VPS9-ankyrin-repeat protein (Varp) in the trafficking of tyrosinase-related protein 1 in melanocytes. J. Biol. Chem. 286, 7507-7521.2011
  • ・Itoh T, Kanno E, Uemura T, Waguri S, and Fukuda M.
    Fukuda M (2011) OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation. J. Cell Biol. 192, 839-853.2011
  • ・Matsuoka H, Harada K, Nakamura J, Fukuda M, and Inoue M.
    Differential distribution of synaptotagmin-1, -4, -7, and -9 in rat adrenal chromaffin cells. Cell Tissue Res. 344, 41-50.2011
  • ・Beaumont KA, Hamilton NA, Moores MT, Brown DL, Ohbayashi N, Cairncross O, Cook AL, Smith AG, Misaki R, Fukuda M, Taguchi T, Sturm RA, and Stow JL.
    The recycling endosome protein Rab17 regulates melanocytic filopodia formation and melanosome trafficking. Traffic 12, 627-643.2011
  • ・Sasakawa N, Ohara-Imaizumi M, Fukuda M, Kabayama H, Mikoshiba K, and Kumakura K.
    Dissociation of inositol polyphosphates from the C2B domain of synaptotagmin facilitates spontaneous release of catecholamines in adrenal chromaffin cells: A suggestive evidence of a fusion clamp by synaptotagmin. Neuropharmacology 60, 1364-1370.2011
  • ・Egami Y, Fukuda M, and Araki N.
    Rab35 regulates phagosome formation through recruitment of ACAP2 in macrophages during FcγR-mediated phagocytosis. J. Cell Sci. 124, 3557-3567.2011
  • ・Vinet AF, Jananji S, Turco SJ, Fukuda M, and Descoteaux A.
    Exclusion of synaptotagmin V at the phagocytic cup by Leishmania donovani lipophosphoglycan results in decreased promastigote internalization. Microbiology 157, 2619-2628.2011
  • ・Matsui T, Itoh T, and Fukuda M.
    Small GTPase Rab12 regulates constitutive degradation of transferrin receptor. Traffic 12, 1432-1443.2011
  • ・Fukuda M, Kobayashi H, Ishibashi K, and Ohbayashi N.
    Genome-wide investigation of the Rab binding activity of RUN domains: Development of a novel tool that specifically traps GTP-Rab35. Cell Struct. Funct. 36, 155-170.2011
  • ・Zhang L, Yu K, Robert KW, DeBolt KM, Hong N, Tao JQ, Fukuda M, Fisher AB, and Huang S.
    Rab38 targets to lamellar bodies and normalizes their sizes in lung alveolar type II epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 301, L461-L477.2011
  • ・Imai A, Yoshie S, Ishibashi K, Haga-Tsujimura M, Nashida T, Shimomura H, and Fukuda M.
    EPI64 protein functions as a physiological GTPase-activating protein for Rab27 protein and regulates amylase release in rat parotid acinar cells. J. Biol. Chem. 286, 33854-33862.2011
  • ・Doi H, Yoshida K, Yasuda T, Fukuda M, Morita H, Ikeda SI, Kato R, Tsurusaki Y, Miyake N, Saitsu H, Sakai H, Miyatake S, Shiina M, Nukina N, Koyano S, Tsuji S, Kuroiwa Y, and Matsumoto N.
    Exome sequencing reveals a homozygous SYT14 mutation in adult-onset autosomal recessive spinocerebellar ataxia with psychomotor retardation. Am. J. Hum. Genet. 89, 320-327.2011
  • ・Ishibashi K, Fujita N, Kanno E, Omori H, Yoshimori T, Itoh T, and Fukuda M.
    Atg16L2, a novel isoform of mammalian Atg16L that is not essential for canonical autophagy despite forming an Atg12–5-16L2 complex. Autophagy 7, 1500-1513.2011
  • ・Fukuda M .
    TBC proteins: GAPs for mammalian small GTPase Rab? Biosci. Rep. 31, 159-168.2011
  • ・Mori Y , and Fukuda M.
    Synaptotagmin IV acts as a multi-functional regulator of Ca2+-dependent exocytosis. Neurochem. Res. 36, 1222-1227.2011
  • ・Ishido N, Kobayashi H, Sako Y, Arai T, Fukuda M,, and Nakamura T.
    How to make FRET biosensors for Rab family GTPases. Biosensors - Emerging Materials and Applications (Serra, P. A. ed.), INTECH, Rijeka, Croatia, pp81-98.2011
  • ・Itoh T , and Fukuda M.
    A possible role of Atg8 homologues as a scaffold for signal transduction. Autophagy 7, 1080-1081.2011
  • ・Matsui T , and Fukuda M.
    Small GTPase Rab12 regulates transferrin receptor degradation: Implications for a novel membrane trafficking pathway from recycling endosomes to lysosomes. Cell. Logistics 1, 139-142.2011
  • ・Fukuda M .
    メラニン色素輸送の仕組み解明から美白研究への応用ー「膜輸送」研究が切り開く新たなアプローチー. 學士會会報, 888, 66-72.2011
  • ・村松慎介, 水谷友紀, 福田光則(Fukuda M).
    メラノソーム輸送機構に基づいた美白アプローチ. フレグランスジャーナル (FRAGRANCE JOURNAL), 39, 19-24.2011
  • ・Ko H.W, Norman R.X, Tran J, Fuller K.P, Fukuda M, and Eggenschwiler J.T.
    Broad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transduction. Dev. Cell, 18, 237-247.2009.PMID: 20159594
  • ・Kanno E, Ishibashi K, Kobayashi H, Matsui T, Ohbayashi N, and Fukuda M.
    Comprehensive screening for novel Rab-binding proteins by GST pull-down assay using 60 different mammalian Rabs. Traffic 11, 491-507.2010
  • ・Tsutsumi K, Takano T, Endo R, Fukuda M, Ohshima T, Tomomura M, and Hisanaga S.
    Phosphorylation of AATYK1 by Cdk5 suppresses its tyrosine phosphorylation. PLoS One 5, e10260.2010
  • ・Schlager MA, Kapitein LC, Grigoriev I, Burzynski GM, Wulf PS, Keijzer N, de Graaff E, Fukuda M, Shepherd IT, Akhmanova A, and Hoogenraad CC.
    Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein-1 (BICDR-1) regulates neuritogenesis. EMBO J. 29, 1637-1651.2010
  • ・Sato M, Mori Y, Matsui T, Aoki R, Oya M, Yanagihara Y, Fukuda M, and Tsuboi T.
    Role of the polybasic sequence in the Doc2α C2B domain in dense-core vesicle exocytosis in PC12 cells. J. Neurochem. 114, 171-181.2010
  • ・Ohbayashi N, Mamishi S, Ishibashi K, Maruta Y, Pourakbari B, Tamizifar B, Mohammadpour M, Fukuda M, and Parvaneh N.
    Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2. Pigment Cell Melanoma Res. 23, 365-374.2010
  • ・Takano T, Tsutsumi K, Saito T, Asada A, Tomomura M, Fukuda M, and Hisanaga S.
    AATYK1A phosphorylation by Cdk5 regulates the recycling endosome pathway. Genes Cells. 15, 783-797.2010
  • ・Harada K, Matsuoka H, Nakamura J, Fukuda M, and Inoue M.
    Storage of GABA in chromaffin granules and not in synaptic-like microvesicles in rat adrenal medullary cells. J. Neurochem. 114, 617-626.2010
  • ・Fukuda M .
    How can mammalian Rab small GTPases be comprehensively analyzed?: Development of new tools to comprehensively analyze mammalian Rabs in membrane traffic. Histol. Histopathol. 25, 1473-1480.2010
  • ・Fukuda M .
    美白研究の新たな展開〜小胞輸送研究が切り開く新しい美白へのアプローチ〜. まなびの杜「特集」, 53, 3-4.2010
  • ・畑友紀, 高山明美, 近藤千春, 板倉研, 福田光則(Fukuda M).
    「Slac2-aタンパク質量低減剤、myosin Vaタンパク質量低減剤、及びSlp2-aタンパク質量低減剤」 特願2009-294615（平成21年12月25日）
  • ・Lico D.T.P, Rosa J.C, DiGiorgis J.A, deVasconcelos E.J.R, Casaletti L, Tauhata S.B.F, Baqui M.M.A, Fukuda M, Moreira J.E , and R E. Larson.
    A novel 65 kDa RNA-binding protein in squid presynaptic terminals. Neuroscience,166(1):73-83.2009.PMID: 20004709
  • ・Ostrowski M, Carmo N.B, Krumeich S, Fanget I, Raposo G, Savina A, Moita C.F, Schauer K, Hume A.N, Freitas R.P, Goud B, Benaroch P, Hacohen N, Fukuda M, Desnos C, Seabra M.C, Darchen F, Amigorena S, Moita L.F, and Thery C.
    Rab27a and Rab27b control different steps of the exosome secretion pathway. Nature Cell Biol.,19-30; sup pp 1-13.2009.PMID: 19966785
  • ・Tsuboi T, Kitaguchi T, Karasawa S, Fukuda M, and Miyawaki A.
    Age-dependent preferential dense-core vesicle exocytosis in neuroendocrine cells revealed by newly developed monomeric fluorescent timer protein. Mol. Biol. Cell, 21(1):87-94.2009.PMID: 19889833
  • ・Vinet A. F, Fukuda M, Turco S.J, and Descoteaux A.
    The Leishmania donovani lipophosphoglycan excludes the vesicular proton-ATPase from phagosomes by impairing the recruitment of Synaptotagmin V. PLoS Pathog. 5, e1000628.2009.PMID: 19834555
  • ・Terabayashi T, Funato Y, Fukuda M, and Miki H.
    A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5). J. Biol. Chem. 284, 26716-26724.2009.PMID: 19643732
  • ・Imai A, Yoshie S, Nashida T, Fukuda M , and Shimomura H.
    Redistribution of small GTP-binding protein, Rab27B, in rat parotid acinar cells after stimulation with isoproterenol. Eur. J. Oral Sci. 117, 224–230.2009.PMID: 19583748
  • ・Fukuda M .
    “Rab27Aエフェクター分子群によるメラノソーム輸送の分子メカニズムの解明” 表面, 47(6), 22-30.2009.
  • ・Maekawa F, Tsuboi T, Fukuda M, and Pellerin L.
    Regulation of the intracellular distribution, cell surface expression, and protein levels of AMPA receptor GluR2 subunits by the monocarboxylate transporter MCT2 in neuronal cells. J. Neurochem. 109, 1767-1778.2009.PMID: 19457092
  • ・Tamura K, Ohbayashi N, Maruta Y, Kanno E, Itoh T, and Fukuda M.
    Varp is a novel Rab32/38-binding protein that regulates Tyrp1 trafficking in melanocytes. Mol. Biol. Cell 20, 2900-2908.2009.PMID: 19403694
  • ・Tambe Y, Yamamoto A, Isono T, Chano T, Fukuda M, and Inoue H.
    The drs tumor suppressor is involved in the maturation process of autophagy induced by low serum. Cancer Lett. 283, 74-83.2009.PMID: 19368996
  • ・Fukuda M .
    “メラノソーム輸送を司る分子群” 太陽紫外線防御研究委員会学術報告, 19(1), 33-37.
  • ・板倉研, 高山明美, 近藤千春, 福田光則(Fukuda M).
    「Slp-2aタンパク質低減剤、及びミオシン-5aタンパク質低減剤」 特願2009-075485（平成21年3月26日）
  • ・Arimura N, Kimura T, Nakamuta S, Taya S, Funahashi Y, Hattori A, Shimada A, Ménager C, Kawabata S, Fujii K, Iwamatsu A, Segal R.A, Fukuda M, and Kaibuchi K.
    Anterograde transport of TrkB in axons is mediated by direct interaction with Slp1 and Rab27. Dev. Cell 16, 675-686.2009.PMID: 19460344
  • ・Imai A, Fukuda M, Yoshie S, Nashida T, and Shimomura H.
    Redistribution of Rab27-specific effectors Slac2-c, but not Slp4-a, afterisoproterenol-stimulation in rat parotid acinar cells. Arch Oral Biol, 54(4), 361-368.2009.PMID: 19185850
  • ・Miyakawa K, Ryo A, Murakami T, Ohba K, Yamaoka S, Fukuda M, Guatelli J, and Yamamoto N.
    BCA2/Rabring7 promotes tetherin-dependent HIV-1 restriction. PLoS Pathog. 5, e1000700.2009
  • ・Ishibashi K, Kanno E, Itoh T, and Fukuda M.
    Identification and characterization of a novel Tre-2/Bub2/Cdc16 (TBC) protein that possesses Rab3A-GAP activity. Genes Cells 14, 41-52.2009.PMID: 19077034
  • ・Itoh Takashi , and Fukuda Mitsunori.
    低分子量Gタンパク質Rabとエフェクター―その特異性と普遍性―. 蛋白質核酸酵素増刊号「メンブレントラフィックの奔流ー分子から細胞，そして個体へ」, 53 (16), 2065-2070.2008
  • ・Vinet AF, Fukuda M, and Descoteaux A.
    The exocytosis regulator Synaptotagmin V controls phagocytosis in macrophages. J Immunol, 181:5289-5295.2008.PMID: 18832684
  • ・Fukuda M .
    Rabファミリーと細胞内小胞輸送. 生体の科学, 59(5), 360-361.
  • ・Kukimoto-Niino M, Sakamoto A, Kanno E, Hanawa-Suetsugu K, Terada T, Shirouzu M, Fukuda M, and Yokoyama S.
    Structural basis for the exclusive specificity of Slac2-a/melanophilin for the Rab27 GTPases. Structure, 16:1478-1490.2008.PMID: 18940604
  • ・Yu E, Kanno E, Choi S, Sugimori M, Moreira JE, Llinás RR , and Fukuda M.
    Role of Rab27 in synaptic transmission at the squid giant synapse. Proc Natl Acad Sci USA, 105:16003-16008.2008.PMID: 18840683
  • ・Kesari A, Fukuda M, Knoblach S, Bashir R, Nader GA, Rao D, Nagaraju K , and Hoffman EP.
    Dysferlin deficiency shows compensatory induction of Rab27A/Slp2a that may contribute to inflammatory onset. Am J Pathol, 173:1476-1487.2008.PMID: 18832576
  • ・Herrero-Turrión MJ, Calafat J, Janssen H, Fukuda M, and Mollinedo F.
    Rab27a regulates exocytosis of tertiary and specific granules in human neutrophils. J Immunol, 181:3793-3803.2008.PMID: 18768832
  • ・Fukuda M .
    Regulation of secretory vesicle traffic by Rab small GTPases. Cell Mol Life Sci, 65:2801-2813.2008.PMID: 18726178
  • ・Fukuda M , and Itoh T.
    Direct link between Atg protein and small GTPase Rab: Atg16L functions as a potential Rab33 effector in mammals. Autophagy, 4:824-826.2008.PMID: 18670194
  • ・Itoh T, Fujita N, Kanno E, Yamamoto A, Yoshimori T , and Fukuda M.
    Golgi-resident small GTPase Rab33B interacts with Atg16L and modulates autophagosome formation. Mol Biol Cell, 19:2916-2925.2008.PMID: 18448665
  • ・Saegusa C, Kanno E, Itohara S , and Fukuda M.
    Expression of Rab27B-binding protein Slp1 in pancreatic acinar cells and its involvement in amylase secretion. Arch Biochem Biophys, 475:87-92.2008.PMID: 18477466
  • ・Patino-Lopez G, Dong XY, Ben-Aissa K, Bernot KM, Itoh T, Fukuda M, Kruhlak MJ, Samelson LE , and Shaw S.
    Rab35 and its GAP EPI64C in T cells regulate receptor recycling and immunological synapse formation. J Biol Chem, 283:18323-18330.2008.PMID: 18450757
  • ・Martin D, Allagnat F, Chaffard G, Caille D, Fukuda M, Regazzi R, Abderrahmani A, Waeber G, Meda P, Maechler P , and Haefliger J-A.
    Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic β cells. Diabetologia, 51:1429-1439.2008.PMID: 18385973
  • ・Sano H, Roach WG, Peck GR, Fukuda M, and Lienhard GE.
    Rab10 in insulin-stimulated GLUT4 translocation. Biochem J, 411:89-95.2008.PMID: 18076383
  • ・板倉研, 畑友紀, 成英次, 高山明美, 福田光則(Fukuda M).
    「メラノソーム輸送阻害剤、及び皮膚外用剤」 特願2008-056389（平成20年3月6日）
  • ・Fujita N, Itoh T, Omori H, Fukuda M, Noda T, and Yoshimori T.
    The Atg16L complex specifies the site of LC3 lipidation for membrane biogenesis in autophagy. Mol Biol Cell, 19:2092-2100.2008.PMID: 18321988
  • ・Fukuda M , and Sagi-Eisenberg R.
    Confusion in the nomenclature of synaptotagmins V and IX: which is which? Calcium Binding Proteins, 3:1-4.
  • ・Holt O, Kanno E, Bossi G, Booth S, Daniele T, Santoro A, Arico M, Saegusa C, and Fukuda M, Griffiths GM.
    Slp1 and Slp2-a localize to the plasma membrane of CTL and contribute to secretion from the immunological synapse. Traffic 9, 446-457. 2008 Feb 21.
    細胞傷害性T細胞は標的細胞と免疫シナプスを形成し、溶菌性顆粒からの放出により標的細胞を殺傷する。この放出過程には低分子量Gタンパク質Rab27Aが関与することが知られている。本論文では、Rab27Aエフェクターの一種Slp2-aが免疫シナプスに集積し、標的細胞の殺傷に関与することを明らかにした。
  • ・Fujibayashi A, Taguchi T, Misaki R, Ohtani M, Dohmae N, Takio K, Yamada M, Gu J, Yamakami M, Fukuda M, Waguri S, Uchiyama Y, Yoshimori T , and Sekiguchi K.
    Human RME-8 is involved in membrane trafficking through early endosomes. Cell Struct. Funct 33, 35-50. 2008 Feb 6.
    RME-8はDnaJドメインを持つ線虫からヒトまで保存されたタンパク質で、エンドサイトーシス過程への関与が示唆されている。本論文では、ヒトRME-8が初期エンドソーム上に存在し、初期エンドソームを介する膜輸送を制御することを明らかにした。
  • ・Fukuda M, Kanno E, Ishibashi K, Itoh T, and Fukuda M.
    Large-scale screening for novel Rab effectors reveals unexpected broad Rab-binding specificity. Mol. Cell. Proteomics 7, 1031-1042. 2008 Feb 6.
    本論文では、低分子量Gタンパク質Rab1〜Rab30のエフェクター分子をRab two-hybrid panelを用いて網羅的にスクリーニングした。その結果、Rabとエフェクター分子の対応関係は以前考えられていた以上に複雑であることが明らかとなった。
  • ・Frittoli E, Palamidessi A, Pizzigoni A, Lanzetti L, Garre M, Fukuda M, Di Fiore PP, Scita G, and Confalonieri S.
    The primate-specific protein TBC1D3 is required for optimal macropinocytosis in a novel ARF6 dependent pathway. Mol. Biol. Cell 19, 1304-1316. 2008 Jan 16.
    TBC1D3はTBCドメインと呼ばれるRab-GAP (GTPase-activating protein）ドメインを持つタンパク質である。TBC1D3は他のTBCドメインを持つ分子とは異なりGAP活性を示さず、Arf6に依存したマクロピノサイトーシスに関与することが本論文により明らかとなった。
  • ・Fukuda M .
    Rab27による分泌小胞の輸送制御メカニズム. ブレインサイエンスレビュー2008（ブレインサイエンス振興財団）, 91-106
  • ・Fukuda M .
    シナプトタグミン. （p.428）, PHドメイン. (p.709-110). 分子細胞生物学辞典（第２版）東京化学同人.2008
  • ・Kanno E , and Fukuda M.
    Increased plasma membrane localization of O-glycosylation-deficient mutant of synaptotagmin I in PC12 cells. J.Neurosci. Res.86, 1036-1043.2008. PMID: 18058942
    シナプトタグミン1はシナプス小胞上に豊富に存在し、神経伝達物質放出の際のカルシウムセンサーとして機能する。シナプトタグミン1分子のシナプス小胞への局在化はその機能を果たす上で不可欠と考えられるが、これまでその分子機構は十分に解明されていなかった。本論文では、シナプトタグミン1分子のO糖鎖修飾に着目し、O糖鎖を欠損する変異体では細胞膜にターゲットしやすいことを明らかにした。
  • ・Mori Y, Higuchi M, Hirabayashi Y, Fukuda M, and Gotoh Y.
    JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release. EMBO J, 27:76-87.2008.PMID: 18046461
  • ・Fukuda M .
    Rabファミリータンパク質による膜輸送制御の特異性と多様性. 生化学,79,1046-51,2007
  • ・Mori Y, Higuchi M, Hirabayashi Y, Fukuda M, and Gotoh Y.
    JNK mediates Syt 4 localization to mature secretory vesicles and enhances Ca2+-evoked release. EMBO J., in press. PMID: 18046461
    PC12細胞を神経成長因子（NGF）で処理すると、伝達物質の放出能が増大することが知られているが、その分子機構の詳細はこれまで謎に包まれていた。本論文では、NGF刺激により活性化されたJNKが、カルシウムセンサー蛋白質の一つシナプトタグミン4をリン酸化することを見いだした。このリン酸化によりシナプトタグミン4分子は成熟した分泌小胞上へとソーティングされ、伝達物質放出の増大に寄与することが初めて明らかとなった。
  • ・Gauthier BR, Duhamel DL, Iezzi M, Theander S, Saltel F, Fukuda M, Wehrle-Haller B , and Wollheim C.B.
    Synaptotagmin VII splice variants α,β, and δare expressed in pancreatic β-cells and regulate insulin exocytosis. FASEB J, 22:194-206.2008.PMID: 17709608
  • ・Tsuboi T , and Fukuda M.
    Synaptotagmin VII modulates the kinetics of dense-core vesicle exocytosis in PC12 cells. Genes Cells 12, 511-519.2007
  • ・Hashii M, Fukuda M, Nomura H, Ito N, Takahashi H, Hattori S, Mikoshiba K, Noda M, and Higuchi Y.
    Up-regulation of ras-GAP genes is reversed by a MEK inhibitor and doxorubicin in v-Ki-ras transformed NIH/3T3 fibroblasts. Biochem. Biophys. Res. Commun. 356, 374-380.2007
  • ・Sano H, Eguez L, Teruel MN, Fukuda M, Chuang TD, Chavez JA, Lienhard GE, and McGraw TE.
    Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane. Cell Metab. 5, 293-303.2007
  • ・Haberman Y, Ziv I, Gorzalczany Y, Hirschberg K, Mittleman L, Fukuda M, and Sagi-Eisenberg R.
    Synaptotagmin (Syt) IX is an essential determinant for protein sorting to secretory granules in mast cells. Blood 109, 3385-3392.2007
  • ・Musch MW, Arvans DL, Walsh-Reitz MM, Uchiyama K, Fukuda M, and Chang EB.
    Synaptotagmin I binds intestinal epithelial NHE3 and mediates cyclic AMP- and Ca2+-induced endocytosis by recruitment of AP2 and clathrin. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G1549-1558.2007
  • ・Brunner Y, Cout醇P Y, Iezzi M, Foti M, Fukuda M, Hochstrasser D, Wollheim CB, and Sanchez J-C.
    Proteomic analysis of insulin secretory granules. Mol. Cell. Proteomics 6, 1007-1017.2007
  • ・Takahashi M, Murate M, Fukuda M, Sato SB, Ohta A, and Kobayashi T.
    Cholesterol controls lipid endocytosis through rab11. Mol. Biol. Cell 18, 2667-2677.2007
  • ・Misaki R, Nakagawa T Fukuda M, Taniguchi N, and Taguchi T.
    Spatial segregation of degradation- and recycling-trafficking pathways in COS-1 cells. Biochem. Biophys. Res. Commun. 360, 580-585.2007
  • ・Swiatecka-Urban A, Talebian L, Kanno E, Moreau-Marquis S, Coutermarsh B, Hansen K, Karlson KH, Barnaby R, Cheney RE, Langford GM, Fukuda M, and Stanton B A.
    Myosin Vb is required for trafficking of cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells. J. Biol. Chem. 282, 23725-23736.2007
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